SN 38-d3 Lactone - Names and Identifiers
SN 38-d3 Lactone - Physico-chemical Properties
Molecular Formula | C22H20N2O5
|
Molar Mass | 392.4046 |
Melting Point | 227-233°C (dec.) |
Storage Condition | -20°C Freezer |
SN 38-d3 Lactone - Introduction
SN-38-D3(SN-38-D3) is a chemical reagent that is a deuterated derivative of 7-ethyl-10-hydroxycamptothecin (SN-38). SN-38 is a natural product from Camptotheca acuminate, which has strong anticancer activity.
SN-38-D3 has properties and uses similar to SN-38, and it is often used as an internal standard in nuclear magnetic resonance (NMR) research. It has a wide range of applications in the field of pharmacokinetics and drug analysis. SN-38-D3 can be used as a standard material to quantitatively monitor the metabolic process of SN-38 in the body, as well as for drug development and pharmacodynamic studies.
The method of preparing SN-38-D3 usually involves reacting unlabeled SN-38 with a reagent having a deuteroethyl group to replace the hydrogen atom in the SN-38. The preparation process needs to pay attention to safe operation, avoid contact with the skin and inhalation into the respiratory system. When using SN-38-D3 in chemical laboratories, it is necessary to follow relevant safety procedures and personal protective measures.
In General, SN-38-D3 is a commonly used chemical reagent used to study the metabolic process and pharmacokinetics of SN-38, and has a wide range of application prospects. However, it is necessary to pay attention to the safety during use.
Last Update:2024-04-09 19:05:58